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Episode 1 - Testosterone

Testosterone Podcast Bibliography of References

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  1. Albert, S. G., & Morley, J. E. (2016). Testosterone therapy, association with age, initiation and mode of therapy with cardiovascular events: a systematic review. Clinical endocrinology, 85(3), 436-443.

  2. Alexandersen, P., & Christiansen, C. (2004). The aging male: testosterone deficiency and testosterone replacement. An up-date. Atherosclerosis, 173(2), 157-169.

  3. Amore, M., Innamorati, M., Costi, S., Sher, L., Girardi, P., & Pompili, M. (2012). Partial androgen deficiency, depression, and testosterone supplementation in aging men. International journal of endocrinology, 2012(1), 280724.

  4. Alsiö, J., Birgner, C., Björkblom, L., Isaksson, P., Bergström, L., Schiöth, H. B., & Lindblom, J. (2009). Impact of nandrolone decanoate on gene expression in endocrine systems related to the adverse effects of anabolic androgenic steroids. Basic & clinical pharmacology & toxicology, 105(5), 307-314.

  5. Baas, W., & Köhler, T. S. (2016). Testosterone replacement therapy and voiding dysfunction. Translational andrology and urology, 5(6), 890.

  6. Bagatell, C. J., Heiman, J. R., Rivier, J. E., & Bremner, W. J. (1994). Effects of endogenous testosterone and estradiol on sexual behavior in normal young men. The Journal of Clinical Endocrinology & Metabolism, 78(3), 711-716.

  7. Bain, J. (2010). Testosterone and the aging male: to treat or not to treat?. Maturitas, 66(1), 16-22.

  8. Biolabs, A., Paliwal, A., Kraemer, B., Shah, D., Basera, I., Mukim, A., ... & Satia, M. (2024). Effect of a Phytochemical formulation on Muscle fatigue, Energy, Recovery in Delayed Onset Muscle Soreness (DOMS), inflammation and Stress in Healthy Subjects: Results from a Randomized Placebo Controlled Study. Journal of Food Science and Nutrition Research, 7, 131-142.

  9. Brooks, S. C., Wappler, N. L., Corombos, J. D., Doherty, L. M., & Horwitz, J. P. (1987). Estrogen structure-receptor function relationships. Recent advances in steroid hormone action, 443-466.

  10. Caplan, M. J. (2019). Everything you always wanted to know about β3-AR*(* but were afraid to ask). Cells, 8(4), 357.

  11. Capparelli, C., Chimento, A., Panza, S., Catalano, S., Lanzino, M., ... & Andò, S. (2012). Nandrolone and stanozolol upregulate aromatase expression and further increase IGF-I-dependent effects on MCF-7 breast cancer cell proliferation. Molecular and cellular endocrinology, 363(1-2), 100-110.

  12. Cauley, J. A. (2015). Estrogen and bone health in men and women. Steroids, 99, 11-15.

  13. Chen, Jen‐Jih, and Hong‐Chiang Chang. "By modulating androgen receptor coactivators, daidzein may act as a phytoandrogen." The Prostate 67.5 (2007): 457-462.

  14. CHENG, Z. G., LIN, Y. C., YU, D. Q., JIANG, S. Q., ZHOU, G. L., & JIANG, Z. Y. (2005). EFFECTS OF DAIDZEIN ON GROWTH PERFORMANCE AND ITS POTENTIAL MECHANISM IN FINISHING PIGS [J]. Acta Zoonutrimenta Sinica, 1, 007.

  15. Chimento, A., Sirianni, R., Zolea, F., De Luca, A., Lanzino, M., Catalano, S., ... & Pezzi, V. (2012). Nandrolone and stanozolol induce Leydig cell tumor proliferation through an estrogen‐dependent mechanism involving IGF‐I system. Journal of cellular physiology, 227(5), 2079-2088.

  16. Crespi, F., Pagliacci, E., Rocchini, G. M., Bianchi, R., Salmona, M., Garattini, S., & Mussini, E. (1979). Esterase activity of rat muscle. European Journal of Drug Metabolism and Pharmacokinetics, 4, 175-177. Schena, G., & 

  17. Davey, R. A., & Grossmann, M. (2016). Androgen receptor structure, function and biology: from bench to bedside. The clinical biochemist reviews, 37(1), 3.

  18. Elfverson, M., Johansson, T., Zhou, Q., Le Grevès, P., & Nyberg, F. (2011). Chronic administration of the anabolic androgenic steroid nandrolone alters neurosteroid action at the sigma-1 receptor but not at the sigma-2 or NMDA receptors. Neuropharmacology, 61(7), 1172-1181.

  19. Erdman, J. W., Balentine, D., Arab, L., Beecher, G., Dwyer, J. T., Folts, J., ... & Messina, M. (2007). Flavonoids and heart health: proceedings of the ILSI North America flavonoids workshop, May 31–June 1, 2005, 

  20. Washington, DC. The Journal of nutrition, 137(3), 718S-737S.

  21. Fenner, A. (2019). A new class of AR antagonists?. Nature Reviews Urology, 16(3), 146-147.

  22. Forsdahl, G., Vatne, H. K., Geisendorfer, T., & Gmeiner, G. (2013). Screening of testosterone esters in human plasma. Drug Testing and Analysis, 5(11-12), 826-833.

  23. Forsdahl, G., Zanitzer, K., Erceg, D., & Gmeiner, G. (2020). Quantification of endogenous steroid sulfates and glucuronides in human urine after intramuscular administration of testosterone esters. Steroids, 157, 108614.

  24. Fragkaki, A. G., Angelis, Y. S., Koupparis, M., Tsantili-Kakoulidou, A., Kokotos, G., & Georgakopoulos, C. (2009). Structural characteristics of anabolic androgenic steroids contributing to binding to the androgen receptor and to their anabolic and androgenic activities: applied modifications in the steroidal structure. Steroids, 74(2), 172-197.

  25. Freedland, S. J., Eastham, J., & Shore, N. (2009). Androgen deprivation therapy and estrogen deficiency induced adverse effects in the treatment of prostate cancer. Prostate cancer and prostatic diseases, 12(4), 333-338.

  26. FUJIOKA, M., SHINOHARA, Y., BABA, S., IRIE, M., & INOUE, K. (1986). Pharmacokinetic properties of testosterone propionate in norman men. The Journal of Clinical Endocrinology & Metabolism, 63(6), 1361-1364.

  27. Georgieva, K. N., & Boyadjiev, N. P. (2004). Effects of nandrolone decanoate on VO2max, running economy, and endurance in rats. Medicine & Science in Sports & Exercise, 36(8), 1336-1341.

  28. Guojie, W., Zhengkang, H., & Weihua, C. (1995). EFFECTS OF DAIDZEIN ON MUSCLE GROWTH AND SOME ENDOGENOUS HORMONE LEVELS IN RATS [J]. ZOOLOGICAL RESEARCH, 1.

  29. Hackett, G., Cole, N., Bhartia, M., Kennedy, D., Raju, J., & Wilkinson, P. (2013). Testosterone replacement therapy with long‒acting testosterone undecanoate improves sexual function and quality‒of‒life parameters vs. placebo in a population of men with type 2 diabetes. The journal of sexual medicine, 10(6), 1612-1627.

  30. Hayden, J. M., Bergen, W. G., & Merkel, R. A. (1992). Skeletal muscle protein metabolism and serum growth hormone, insulin, and cortisol concentrations in growing steers implanted with estradiol-17β, trenbolone acetate, or estradiol-17β plus trenbolone acetate. Journal of Animal Science, 70(7), 2109-2119.

  31. Han, S., Jeon, Y. J., Lee, T. Y., Park, G. M., Park, S., & Kim, S. C. (2022). Testosterone is associated with abdominal body composition derived from computed tomography: a large cross sectional study. Scientific Reports, 12(1), 22528.

  32. Handelsman, D. J., Hirschberg, A. L., & Bermon, S. (2018). Circulating testosterone as the hormonal basis of sex differences in athletic performance. Endocrine reviews, 39(5), 803-829.

  33. Harris, W. P., Mostaghel, E. A., Nelson, P. S., & Montgomery, B. (2009). Androgen deprivation therapy: progress in understanding mechanisms of resistance and optimizing androgen depletion. Nature clinical practice Urology, 6(2), 76-85.

  34. Hartgens, F., & Kuipers, H. (2004). Effects of androgenic-anabolic steroids in athletes. Sports medicine, 34, 513-554.

  35. Healy, M. L., Gibney, J., Pentecost, C., Wheeler, M. J., & Sonksen, P. H. (2014). Endocrine profiles in 693 elite athletes in the postcompetition setting. Clinical endocrinology, 81(2), 294-305.

  36. Holma, P., & Adlercreutz, H. (1976). Effect of an anabolic steroid (metandienon) on plasma LH, FSH, and testosterone and on the response to intravenous administration of LRH. European Journal of Endocrinology, 83(4), 856-864.

  37. Hooper, D. R., Tenforde, A. S., & Hackney, A. C. (2018). Treating exercise-associated low testosterone and its related symptoms. The Physician and sportsmedicine, 46(4), 427-434.

  38. Huo, S., Scialli, A. R., McGarvey, S., Hill, E., Tügertimur, B., Hogenmiller, A., ... & Fugh-Berman, A. (2016). Treatment of men for “low testosterone”: a systematic review. PloS one, 11(9), e0162480.

  39. Hyyppä, S., Karvonen, U., Räsänen, L. A., Persson, S. G. B., & Pösö, A. R. (1997). Androgen receptors and skeletal muscle composition in trotters treated with nandrolone laureate. Journal of Veterinary Medicine Series A, 44(1‐10), 481-491.

  40. Jain, P., Rademaker, A. W., & Mcvary, K. T. (2000). Testosterone supplementation for erectile dysfunction: results of a meta-analysis. The Journal of urology, 164(2), 371-375.Khaodhiar, Lalita, et al. "Daidzein-rich isoflavone aglycones are potentially effective in reducing hot flashes in menopausal women." Menopause (New York, NY) 15.1 (2008): 125.

  41. Johnson, J. M., Nachtigall, L. B., & Stern, T. A. (2013). The effect of testosterone levels on mood in men: a review. Psychosomatics, 54(6), 509-514.

  42. Kaplan, S. A., Lee, J. Y., O’Neill, E. A., Meehan, A. G., & Kusek, J. W. (2013). Prevalence of low testosterone and its relationship to body mass index in older men with lower urinary tract symptoms associated with benign prostatic hyperplasia. The Aging Male, 16(4), 169-172.

  43. Khosla, S., Melton III, L. J., & Riggs, B. L. (2002). Estrogen and the male skeleton. The Journal of Clinical Endocrinology & Metabolism, 87(4), 1443-1450.

  44. Kuiper, George GJM, et al. "Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor β." Endocrinology 139.10 (1998): 4252-4263

  45. Kurzer, Mindy S., and Xia Xu. "Dietary phytoestrogens." Annual review of nutrition 17.1 (1997): 353-381.

  46. Lee, D. K., & Chang, C. (2003). Expression and degradation of androgen receptor: mechanism and clinical implication. The Journal of Clinical Endocrinology & Metabolism, 88(9), 4043-4054.

  47. Losby, M., Hayes, M., Valfort, A., Walker, J., Xu, W., Zhang, L., ... & Burris, T. P. (2023). The Estrogen Receptor-Related Orphan Receptors (ERRs) Regulate Autophagy through TFEB. bioRxiv, 2023-03.

  48. Lund, B. C., Bever‐Stille, K. A., & Perry, P. J. (1999). Testosterone and andropause: the feasibility of testosterone replacement therapy in elderly men. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 19(8), 951-956.

  49. McBride, J. A., Carson III, C. C., & Coward, R. M. (2016). Testosterone deficiency in the aging male. Therapeutic advances in urology, 8(1), 47-60.

  50. Meyer, H. H. (2001). Biochemistry and physiology of anabolic hormones used for improvement of meat production. Apmis, 109(S103), S336-S344.

  51. Näär, Anders M., Bryan D. Lemon, and Robert Tjian. "Transcriptional coactivator complexes." Annual review of biochemistry 70.1 (2001): 475-501.

  52. Morgentaler, A., Miner, M. M., Caliber, M., Guay, A. T., Khera, M., & Traish, A. M. (2015, February). Testosterone therapy and cardiovascular risk: advances and controversies. In Mayo Clinic Proceedings (Vol. 90, No. 2, pp. 224-251). Elsevier.

  53. Pan, W., Ikeda, K., Takebe, M., & Yamori, Y. (2001). Genistein, daidzein and glycitein inhibit growth and DNA synthesis of aortic smooth muscle cells from stroke-prone spontaneously hypertensive rats. The Journal of nutrition,131(4), 1154-1158.

  54. Partsch, C. J., Weinbauer, G. F., Fang, R., & Nieschlag, E. (1995). Injectable testosterone undecanoate has more favourable pharmacokinetics and pharmacodynamics than testosterone enanthate. European journal of endocrinology, 132(4), 514-519.

  55. Patanè, F. G., Liberto, A., Maria Maglitto, A. N., Malandrino, P., Esposito, M., Amico, F., ... & Montana, A. (2020). Nandrolone decanoate: use, abuse and side effects. Medicina, 56(11), 606.

  56. Pezzolato, M., Botta, M., Baioni, E., Richelmi, G. B., Pitardi, D., Varello, K., ... & Bozzetta, E. (2016). Confirmation of the progesterone receptor as an efficient marker of treatment with 17β-estradiol in veal calves. Food Additives & Contaminants: Part A, 33(1), 60-65.

  57. Phillips, I., Shah, S. I., Duong, T., Abel, P., & Langley, R. E. (2014). Androgen deprivation therapy and the re-emergence of parenteral estrogen in prostate cancer. Oncology & hematology review, 10(1), 42.

  58. Piper, T., Dib, J., Putz, M., Fusshöller, G., Pop, V., Lagojda, A., ... & Thevis, M. (2018). Studies on the in vivo metabolism of the SARM YK11: Identification and characterization of metabolites potentially useful for doping controls. Drug testing and analysis, 10(11-12), 1646-1656.

  59. Pomara, C., Barone, R., Marino Gammazza, A., Sangiorgi, C., Barone, F., Pitruzzella, A., ... & Turillazzi, E. (2016). Effects of nandrolone stimulation on testosterone biosynthesis in leydig cells. Journal of Cellular Physiology, 231(6), 1385-1391.

  60. Rahman, M. S. (2016). The Effects of VO2max on Levels of Testosterone as Males Age (Doctoral dissertation).

  61. Ren, M. Q., Kuhn, G., Wegner, J., Nurnberg, G., Chen, J., & Ender, K. (2001). Feeding daidzein to late pregnant sows influences the estrogen receptor beta and type 1 insulin-like growth factor receptor mRNA expression in newborn piglets. Journal of Endocrinology, 170(1), 129-135.

  62. Richardson, T. E., & Simpkins, J. W. (2012). R-and S-Equol have equivalent cytoprotective effects in Friedreich’s Ataxia. BMC Pharmacology and Toxicology, 13, 1-6.

  63. Rochira, V., Faustini-Fustini, M., Balestrieri, A., & Carani, C. (2000). Estrogen replacement therapy in a man with congenital aromatase deficiency: effects of different doses of transdermal estradiol on bone mineral density and hormonal parameters. The Journal of Clinical Endocrinology & Metabolism, 85(5), 1841-1845.

  64. Russell, N., Cheung, A., & Grossmann, M. (2017). Estradiol for the mitigation of adverse effects of androgen deprivation therapy. Endocrine-related cancer, 24(8), R297-R313.

  65. Saartok, T., Dahlberg, E., & Gustafsson, J. Å. (1984). Relative binding affinity of anabolic-androgenic steroids: comparison of the binding to the androgen receptors in skeletal muscle and in prostate, as well as to sex hormone-binding globulin. Endocrinology, 114(6), 2100-2106.

  66. Sacks, F. M., Lichtenstein, A., Van Horn, L., Harris, W., Kris-Etherton, P., Winston, M., & American Heart Association. Nutrition Committee. (2006). Soy protein, isoflavones, and cardiovascular health an American Heart Association science advisory for professionals from the nutrition committee. Circulation, 113(7), 1034-1044.

  67. Salimi, Z., Moradpour, F., Khajehpour, L., Moazedi, A. A., & Pourmotabbed, A. (2017). The role of aromatase and castration on spatial learning and memory changes by nandrolone. Avicenna Journal of Neuro Psycho Physiology, 4(4), 153-162.

  68. Saunders, F. J., Colton, F. B., & Drill, V. A. (1957). Progesterone-like activity of a series of 19-nortestosterones. Proceedings of the Society for Experimental Biology and Medicine, 94(4), 717-720.

  69. Schena, G., & Caplan, M. J. (2019). Everything you always wanted to know about β3-AR*(* but were afraid to ask). Cells, 8(4), 357.

  70. Schubert, M., Minnemann, T., Hubler, D., Rouskova, D., Christoph, A., Oettel, M., ... & Jockenhovel, F. (2004). Intramuscular testosterone undecanoate: pharmacokinetic aspects of a novel testosterone formulation during long-term treatment of men with hypogonadism. The Journal of Clinical Endocrinology & Metabolism, 89(11), 5429-5434.

  71. Schulster, M., Bernie, A. M., & Ramasamy, R. (2016). The role of estradiol in male reproductive function. Asian journal of andrology, 18(3), 435-440.

  72. Seidman, S. N. (2005). Testosterone deficiency, depression and sexual function in aging men. Psychiatric Times, 22(11), 82-82.

  73. Sharifi, N., Gulley, J. L., & Dahut, W. L. (2005). Androgen deprivation therapy for prostate cancer. Jama, 294(2), 238-244.

  74. Shoskes, J. J., Wilson, M. K., & Spinner, M. L. (2016). Pharmacology of testosterone replacement therapy preparations. Translational andrology and urology, 5(6), 834.

  75. Sternbach, H. (1998). Age-associated testosterone decline in men: clinical issues for psychiatry. American Journal of Psychiatry, 155(10), 1310-1318.

  76. Setchell, K. D., & Clerici, C. (2010). Equol: pharmacokinetics and biological actions. The Journal of nutrition, 140(7), 1363S-1368S.

  77. Sheehan, M. T. (2004). Polycystic ovarian syndrome: diagnosis and management. Clinical medicine and research, 2(1), 13.

  78. Shifren, J. L. (2004, April). The role of androgens in female sexual dysfunction. In Mayo Clinic Proceedings (Vol. 79, No. 4, pp. S19-S24). Elsevier.

  79. Tai, P. J., Huang, Y. H., Shih, C. H., Chen, R. N., Chen, C. D., Chen, W. J., ... & Lin, K. H. (2007). Direct regulation of androgen receptor-associated protein 70 by thyroid hormone and its receptors. Endocrinology, 148(7), 3485-3495.

  80. Tauchen, J., Jurášek, M., Huml, L., & Rimpelová, S. (2021). Medicinal use of testosterone and related steroids revisited. Molecules, 26(4), 1032.

  81. Traish, A. M. (2016). Testosterone therapy in men with testosterone deficiency: are the benefits and cardiovascular risks real or imagined?. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 311(3), R566-R573.

  82. Walsh, J. P., & Kitchens, A. C. (2015). Testosterone therapy and cardiovascular risk. Trends in Cardiovascular Medicine, 25(3), 250-257.

  83. Wibowo, E., Schellhammer, P., & Wassersug, R. J. (2011). Role of estrogen in normal male function: clinical implications for patients with prostate cancer on androgen deprivation therapy. The Journal of urology, 185(1), 17-23.

  84. Wibowo, E., & Wassersug, R. J. (2013). The effect of estrogen on the sexual interest of castrated males: Implications to prostate cancer patients on androgen-deprivation therapy. Critical Reviews in Oncology/Hematology, 87(3), 224-238.

  85. Wu, D., & Gore, A. C. (2010). Changes in androgen receptor, estrogen receptor alpha, and sexual behavior with aging and testosterone in male rats. Hormones and Behavior, 58(2), 306-316.

  86. Yamasaki, K., Sawaki, M., Noda, S., Muroi, T., Takakura, S., Mitoma, H., ... & Yakabe, Y. (2004). Comparison of the Hershberger assay and androgen receptor binding assay of twelve chemicals. Toxicology, 195(2-3), 177-186.

  87. Yarrow, J. F., McCoy, S. C., & Borst, S. E. (2010). Tissue selectivity and potential clinical applications of trenbolone (17β-hydroxyestra-4, 9, 11-trien-3-one): a potent anabolic steroid with reduced androgenic and estrogenic activity. Steroids, 75(6), 377-389.

  88. Yeater, R., Reed, C., Ullrich, I., Morise, A., & Borsch, M. (1996). Resistance trained athletes using or not using anabolic steroids compared to runners: effects on cardiorespiratory variables, body composition, and plasma lipids. British journal of sports medicine, 30(1), 11-14.

  89. Yeh, S., Miyamoto, H., Shima, H., & Chang, C. (1998). From estrogen to androgen receptor: a new pathway for sex hormones in prostate. Proceedings of the National Academy of Sciences, 95(10), 5527-5532.

  90. Yeh, Shuyuan, and Chawnshang Chang. "Cloning and characterization of a specific coactivator, ARA70, for the androgen receptor in human prostate cells." Proceedings of the National Academy of Sciences 93.11 (1996): 5517-5521.

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